Association between interleukin-6 -174 polymorphism and Aggregatibacter actinomycetemcomitans in chronic periodontitis.

doi:10.1902/jop.2010.100084

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Article

Association between interleukin-6 -174 polymorphism and Aggregatibacter actinomycetemcomitans in chronic periodontitis.

Journal of periodontology - 1 Dec 2010

Nibali L, Donos N, Farrell S, Ready D, Pratten J, Tu Y K, D'Aiuto F

Abstract excerpt

BACKGROUND: We previously demonstrated an association between interleukin-6 (IL-6) polymorphisms and the detection of periodontopathogenic bacteria in aggressive and chronic periodontitis on a patient basis (pooled samples). The aim of this study is to comprehensively analyze the relative contribution of IL-6 genetic factors and local (tooth and site) factors on the detection of Aggregatibacter...

Topics

Adult
Aggregatibacter actinomycetemcomitans
Alveolar Bone Loss
Chronic Periodontitis
Cytosine
Dental Plaque
Female
Genotype
Gingival Hemorrhage
Gingival Recession
Guanine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homozygote

Humans

Interleukin-6

Male

Middle Aged

Periodontal Attachment Loss

Periodontal Pocket

Source

Open in PubMed

Identifiers

PMID: 20681812
DOI: 10.1902/jop.2010.100084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20681812-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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