Article
Expression, polymorphism and methylation pattern of interleukin-6 in periodontal tissues.
Immunobiology - 1 Jul 2013
Stefani Florença Abdanur, Viana Michelle Beatriz, Dupim Ana Carolina, Brito João Artur Ricieri, Gomez Ricardo Santiago, da Costa José Eustáquio, Moreira Paula Rocha
Abstract excerpt
Periodontitis is considered an inflammatory disorder of bacterial etiology that results in periodontal tissue destruction, as a result of complex interactions between periodontal pathogens, host and immune response. Genetic and epigenetic mechanisms may modulate the individual response since it i...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Case-Control Studies
- Chronic Periodontitis
- DNA Methylation
- Female
- Gene Expression Regulation
- Gene Frequency
- Genotype
- Gingiva
- Humans
- Interleukin-6
- Leukocytes, Mononuclear
- Male
- Middle Aged
- Polymorphism, Single Nucleotide