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Genetic polymorphisms in interleukin-6 and interleukin-1-beta were associated with dental caries and gingivitis.

Acta odontologica Scandinavica - 1 Mar 2021

Reis Caio Luiz Bitencourt, Barbosa Mariane Carolina Faria, Machado Bárbara Maria de Souza Moreira, Baratto Samantha Schaffer Pugsley, de Lima Daniela Coelho, Paza Aleysson Olímpio, Filho Flares Baratto, Brancher João Armando, Küchler Erika Calvano, de Oliveira Daniela Silva Barroso

Abstract excerpt

OBJECTIVE: Evaluate the association between single nucleotide polymorphisms (SNPs) in Interleukin-6 (IL-6) gene (rs1800795) and in Interleukin-1-beta (IL-1β) gene (rs1143627 and rs1143629) with dental caries and gingivitis in Brazilian children. MATERIAL AND METHODS: Three hundred and fifty-three children aged 8-11 years were included. Visible biofilm and gingival bleeding were evaluated by Community Periodontal...

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PMID: 32643487
DOI: 10.1080/00016357.2020.1788722

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