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Article

Complete physical mapping of IL6 reveals a new marker associated with chronic periodontitis.

Journal of periodontal research - 1 Apr 2017

Farhat S B, de Souza C M, Braosi A P R, Kim S H, Tramontina V A, Papalexiou V, Olandoski M, Mira M T, Luczyszyn S M, Trevilatto P C

Abstract excerpt

BACKGROUND AND OBJECTIVE: Interleukin-6 (IL-6) is a powerful stimulator of osteoclast differentiation and bone resorption. Production of IL-6 is modulated by polymorphisms, and higher levels of this cytokine are found locally in patients with chronic periodontitis. In this study we performed a modern approach - Complete physical mapping of the IL6 gene - to identify the polymorphisms associated with chronic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 27172922
DOI: 10.1111/jre.12389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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