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Article

Comprehensive pathway-based analysis identifies associations of BCL2, GNAO1 and CHD2 with non-obstructive azoospermia risk.

Human reproduction (Oxford, England) - 1 Apr 2014

Qin Yufeng, Ji Juan, Du Guizhen, Wu Wei, Dai Juncheng, Hu Zhibin, Sha Jiahao, Hang Bo, Lu Chuncheng, Xia Yankai, Wang Xinru

Abstract excerpt

STUDY QUESTION: Do genetic variants in known canonical pathways that have been widely suggested to affect spermatogenesis confer susceptibility to non-obstructive azoospermia (NOA)? SUMMARY ANSWER: Rs1406714 in CHD2, rs2126986 in GNAO1 and rs7226979 in BCL2 were associated with NOA in Han Chinese...

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Share to Azoospermia
Share to DNA-Binding Proteins
Share to BCL2 gene
Share to Genome-Wide Association Study
Share to Genotype
Share to GTP-Binding Protein alpha Subunits, Gi-Go
Share to Polymorphism, Single Nucleotide
Share to Proto-Oncogene Proteins c-bcl-2

Source

Identifiers

PMID: 24549219
DOI: 10.1093/humrep/deu013

Genes

BCL2
CHD2
GNAO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24549219-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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