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Article

Genome-wide Loci linked to non-obstructive azoospermia susceptibility may be independent of reduced sperm production in males with normozoospermia.

Biology of reproduction - 1 Feb 2015

Tu Wenling, Liu Yunqiang, Shen Ying, Yan Yuanlong, Wang Xianding, Yang Dong, Li Lei, Ma Yongxin, Tao Dachang, Zhang Sizhong, Yang Yuan

Abstract excerpt

Non-obstructive azoospermia (NOA) is a complex, multifactorial disease. Recent genome-wide association studies (GWAS) have identified eight NOA susceptibility loci at genome-wide significance of P < 5.0 × 10(-8) in Han Chinese from southeastern, northern, and central China. To better understand the role of the variants in conferring NOA risk, we selected four GWAS loci (HLA-DRA rs3129878, PRMT6 rs12097821, SOX5...

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Source

Identifiers

PMID: 25505198
DOI: 10.1095/biolreprod.114.125237

Genes

PEX10
PRMT6
SOX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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