TOMM40 rs2075650 may represent a new candidate gene for vulnerability to major depressive disorder.

doi:10.1038/npp.2014.22

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Article

TOMM40 rs2075650 may represent a new candidate gene for vulnerability to major depressive disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2014

McFarquhar Martyn, Elliott Rebecca, McKie Shane, Thomas Emma, Downey Darragh, Mekli Krisztina, Toth Zoltan G, Anderson Ian M, Deakin J F William, Juhasz Gabriella

Abstract excerpt

Evidence suggests that depression is a risk factor for dementia; however, the relationship between the two conditions is not fully understood. A novel gene (TOMM40) has been consistently associated with Alzheimer's disease (AD), but has received no attention in depression. We conducted a three-level cross-sectional study to investigate the association of the TOMM40 rs2075650 SNP with depression. We recruited a...

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Identifiers

PMID: 24549102
DOI: 10.1038/npp.2014.22
PMCID: PMC4023148

Genes

TOMM40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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