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Article

A genotype-endophenotype-phenotype path model of depressed mood: integrating cognitive and emotional markers.

Journal of integrative neuroscience - 1 Mar 2007

Gatt Justine M, Clark C Richard, Kemp Andrew H, Liddell Belinda J, Dobson-Stone Carol, Kuan Stacey A, Schofield Peter R, Williams Leanne M

Abstract excerpt

AIMS: Following an integrative neuroscience perspective, we propose that cognitive and emotional functions are integrally linked, and that genetic polymorphisms which impact upon neural processes may have complementary effects on these functions. The brain-derived neurotrophic factor (BDNF) 66Met allele may contribute to both cognitive and emotional aspects of the depression phenotype. METHODS: In 374 nonclinical...

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Source

Identifiers

PMID: 17472225
DOI: 10.1142/s0219635207001398

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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