Article
Osteopontin splice variant as a potential marker for metastatic disease in pancreatic adenocarcinoma.
Journal of gastroenterology and hepatology - 1 Jun 2014
Siddiqui Ali A, Jones Elizabeth, Andrade Darren, Shah Apeksha, Kowalski Thomas E, Loren David E, Chipitsyna Galina, Arafat Hwyda A
Abstract excerpt
BACKGROUND AND AIM: Osteopontin (OPN) is a phosphoprotein that activates pathways that induce cancer cell survival and metastasis. Our aim was to examine the expression pattern of OPN splice variants a, b, and c in fine-needle aspirates and to determine their correlation with stage-adjusted pancreatic ductal adenocarcinoma (PDA) survival. METHODS: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) was...
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