Article
Osteopontin Splice Variants Differentially Exert Clinicopathological Features and Biological Functions in Gastric Cancer
1 Jan 2013
Abstract excerpt
PURPOSE: Gastric cancer (GC) remains a leading cause of death worldwide, and an elevated expression of osteopontin (OPN) may correlate with its poor survival. Alternative splicing of OPN can result in three isoforms, OPN-a, OPN-b and OPN-c. The aim of our current study is to examine the expression pattern and biological functions of OPN splice variants in GC. METHODS: Firstly, we evaluated the expression of OPN...
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