Article
Impact of age and body position on the contribution of nitric oxide to femoral artery shear rate: implications for atherosclerosis.
Hypertension (Dallas, Tex. : 1979) - 1 May 2014
Trinity Joel D, Groot H Jonathan, Layec Gwenael, Rossman Matthew J, Ives Stephen J, Richardson Russell S
Abstract excerpt
Reduced shear stress and augmented oscillatory shear rate are associated with the proatherogenic phenotype observed with aging. To date, mechanisms contributing to the age-related alterations in shear rate in humans have only been examined in the conduit vessels of the arm. Therefore, this study sought to examine the contribution of nitric oxide (NO) bioavailability to age-related alterations in shear rate and...
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