Article
Oscillatory shear stress, flow-mediated dilatation, and circulating microparticles at sea level and high altitude.
Atherosclerosis - 1 Jan 2017
Tremblay Joshua C, Thom Stephen R, Yang Ming, Ainslie Philip N
Abstract excerpt
BACKGROUND AND AIMS: Exposing the endothelium to acute periods of imposed oscillatory shear stress reduces endothelial function and elevates circulating microparticles (MPs). Oscillatory shear stress may be especially pathogenic when superimposed on hypoxia, an environmental stimulus that disrupts the endothelial milieu. We examined the effects of acute manipulation of oscillatory shear stress on endothelial...
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