Article
Exploiting the extraordinary genetic polymorphism of ciona for developmental genetics with whole genome sequencing.
Genetics - 1 May 2014
Abdul-Wajid Sarah, Veeman Michael T, Chiba Shota, Turner Thomas L, Smith William C
Abstract excerpt
Studies in tunicates such as Ciona have revealed new insights into the evolutionary origins of chordate development. Ciona populations are characterized by high levels of natural genetic variation, between 1 and 5%. This variation has provided abundant material for forward genetic studies. In the current study, we make use of deep sequencing and homozygosity mapping to map spontaneous mutations in outbred...
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