Article
Mutation studies in ascidians: a review.
Genesis (New York, N.Y. : 2000) - 1 Jan 2015
Crocetta Fabio, Marino Rita, Cirino Paola, Macina Alberto, Staiano Leopoldo, Esposito Rosaria, Pezzotti Maria Rosa, Racioppi Claudia, Toscano Francesco, De Felice Elena, Locascio Annamaria, Ristoratore Filomena, Spagnuolo Antonietta, Zanetti Laura, Branno Margherita, Sordino Paolo
Abstract excerpt
Historically, mutations have had a significant impact on the study of developmental processes and phenotypic evolution. Lesions in DNA are created by artificial methods or detected by natural genetic variation. Random mutations are then ascribed to genetic change by direct sequencing or positional cloning. Tunicate species of the ascidian genus Ciona represent nearly fully realized model systems in which gene...
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