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Article

Diploid genome reconstruction of Ciona intestinalis and comparative analysis with Ciona savignyi.

Genome research - 1 Jul 2007

Kim Jong Hyun, Waterman Michael S, Li Lei M

Abstract excerpt

One of the main goals in genome sequencing projects is to determine a haploid consensus sequence even when clone libraries are constructed from homologous chromosomes. However, it has been noticed that haplotypes can be inferred from genome assemblies by investigating phase conservation in sequenced reads. In this study, we seek to infer haplotypes, a diploid consensus sequence, from the genome assembly of an...

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PMID: 17567986
DOI: 10.1101/gr.5894107
PMCID: PMC1899121

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