Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

5 Jan 2013

Abstract excerpt

The molecular repertoire of macrophages in health and disease can provide novel biomarkers for diagnosis, prognosis, and treatment. Th2-IL-4–activated macrophages (M2) have been associated with important diseases in mice, yet no specific markers are available for their detection in human tissues. Although mouse models are widely used for macrophage research, translation to the human can be problematic and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune cells in cancer
Share to Immune Response and Inflammation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23293084
DOI: 10.1182/blood-2012-06-436212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differencesPMID 23293084Read ↗

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage ActivationSemantic proximity Read ↗

Genomic analyses identify biological processes and functions between M1 and M2 macrophagesSemantic proximity Read ↗

Defining tissue- and disease-associated macrophages using a transcriptome-based classification modelSemantic proximity Read ↗

Integrated proteomic and transcriptomic landscape of macrophages in mouse tissuesSemantic proximity Read ↗

Getting everyone to agree on gene signatures for murine macrophage polarization in vitro.Semantic proximity Read ↗

Macrophage plasticity and polarization: in vivo veritas.Semantic proximity Read ↗

A Gene Expression Analysis of M1 and M2 Polarized Macrophages.Semantic proximity Read ↗

Novel Markers to Delineate Murine M1 and M2 Macrophages.Semantic proximity Read ↗

Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages (LAMs)Semantic proximity Read ↗

Understanding macrophage diversity at the ontogenic and transcriptomic levels.Semantic proximity Read ↗

Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing.Semantic proximity Read ↗

Tissue signatures of human macrophages during homeostasis and activationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.