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Article

A paradigm shift of SERPINA3N in neurobehavioral development and brain injury

2025-09-15

Abstract excerpt

Murine serine protease inhibitor clade A member 3N (SERPINA3N) and its human ortholog SERPINA3 are dysregulated in neurological disorders. SERPINA3N has been proposed as a protective factor, enhancing neurobehavioral development under homeostasis and mitigating neuronal/glial and vascular damage under neurological conditions. Here, we employed powerful, non-invasive genetic tools to revisit the concept of SERPINA3...

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Identifiers and source

Literature Corpus work
82f85721-09cf-5c4a-999c-62a33ca0c9cb
DOI
10.1101/2025.09.09.675167
Open publication

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