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Article

GLUT1 deficiency links nutrient availability and apoptosis during embryonic development.

The Journal of biological chemistry - 12 May 2006

Jensen Penny J, Gitlin Jonathan D, Carayannopoulos Mary O

Abstract excerpt

GLUT1 is essential for human brain development and function, as evidenced by the severe epileptic encephalopathy observed in children with GLUT1 deficiency syndrome resulting from inherited loss-of-function mutations in the gene encoding this facilitative glucose transporter. To further elucidate the pathophysiology of this disorder, the zebrafish orthologue of human GLUT1 was identified, and expression of this...

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Share to bcl-Associated Death Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16543226
DOI: 10.1074/jbc.M601881200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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