Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction.

American journal of physiology. Endocrinology and metabolism - 1 May 2007

Ganguly Amit, McKnight Robert A, Raychaudhuri Santanu, Shin Bo-Chul, Ma Zhigui, Moley Kelle, Devaskar Sherin U

Abstract excerpt

Glucose transporter isoform-3 (GLUT3) is the trophoblastic facilitative glucose transporter. To investigate the role of this isoform in embryonic development, we created a novel GLUT3-null mouse and observed arrested early embryonic development and loss at neurulation stage when both alleles were mutated. This loss occurred despite the presence of other related isoforms, particularly GLUT1. In contrast, when a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Spontaneous
Share to Blastocyst

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic Development

Share to Embryonic Stem Cells

Share to Glucose Tolerance Test

Share to Insulin-Like Growth Factor Binding Protein 3

Share to Insulin-Like Growth Factor I

Share to Placenta

Source

Identifiers

PMID: 17213475
DOI: 10.1152/ajpendo.00344.2006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction.PMID 17213475Read ↗

GLUT3 gene expression is critical for embryonic growth, brain development and survival.Semantic proximity Read ↗

Placental glucose transporter 3 (GLUT3) is up-regulated in human pregnancies complicated by late-onset intrauterine growth restrictionSemantic proximity Read ↗

Essential role of glucose transporter GLUT3 for post-implantation embryonic developmentSemantic proximity Read ↗

Placental Glucose and Amino Acid Transport in Calorie-Restricted Wild-Type and Glut3 Null Heterozygous MiceSemantic proximity Read ↗

Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiencySemantic proximity Read ↗

Glucose transporters in preimplantation developmentSemantic proximity Read ↗

Neural Deletion of Glucose Transporter Isoform 3 Creates Distinct Postnatal and Adult Neurobehavioral Phenotypes.Semantic proximity Read ↗

Peg3 mutational effects on reproduction and placenta-specific gene families.Semantic proximity Read ↗

Peg3 Deficiency Results in Sexually Dimorphic Losses and Gains in the Normal Repertoire of Placental HormonesSemantic proximity Read ↗

Mouse ZIP1 and ZIP3 genes together are essential for adaptation to dietary zinc deficiency during pregnancy.Semantic proximity Read ↗

A Novel Mutant Allele of Pw1/Peg3 Does Not Affect Maternal Behavior or Nursing Behavior.Semantic proximity Read ↗

Regulation of maternal behavior and offspring growth by paternally expressed Peg3.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.