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Article

Interferon lambda alleles predict innate antiviral immune responses and hepatitis C virus permissiveness.

Cell host & microbe - 12 Feb 2014

Sheahan Timothy, Imanaka Naoko, Marukian Svetlana, Dorner Marcus, Liu Peng, Ploss Alexander, Rice Charles M

Abstract excerpt

Hepatitis C virus (HCV) infection can result in viral chronicity or clearance. Although host genetics and particularly genetic variation in the interferon lambda (IFNL) locus are associated with spontaneous HCV clearance and treatment success, the mechanisms guiding these clinical outcomes remain...

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Identifiers

PMID: 24528865
DOI: 10.1016/j.chom.2014.01.007
PMCID: PMC4104123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24528865-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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