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Article

In-depth analyses unveil the association and possible functional involvement of novel RAD51B polymorphisms in age-related macular degeneration.

Age (Dordrecht, Netherlands) - 1 Jun 2014

Chu Xi K, Meyerle Catherine B, Liang Xiaoling, Chew Emily Y, Chan Chi-Chao, Tuo Jingsheng

Abstract excerpt

The contribution of DNA damage to the pathogenesis of age-related macular degeneration (AMD) has been reported. Recently, a genomewide association study detected the association of a single-nucleotide polymorphism (SNP) in RAD51B (rs8017304 A>G) with AMD. RAD51B is involved in recombinational rep...

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Source

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Identifiers

PMID: 24526414
DOI: 10.1007/s11357-014-9627-2
PMCID: PMC4082603

Genes

ARMS2
CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24526414-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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