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Article

RAD51 gene is associated with advanced age-related macular degeneration in Chinese population.

Clinical biochemistry - 1 Nov 2013

Zhou Jie, Wang Dan, Zhang Junjun, Zhang Meixia, Lu Fang, Qiu Guoxian, Zhao Ling, Nguyen Duy H, Luo Hongrong, Cao Guiqun, Zhang Wei, Jiang Wei, Li Gen, Zhang Kang, Zhang Ming, Su Zhiguang

Abstract excerpt

OBJECTIVES: This study aims to investigate whether variations in RAD51, B3GALTL, TNFRSF10A and REST-C4ORF14-POLR2B-IGFBP7 are associated with advanced forms of age-related macular degeneration (AMD) in Chinese population. DESIGN AND METHODS: A total of 119 Chinese patients with AMD and 99 control individuals were recruited. Genomic DNA was extracted from peripheral blood leukocytes. Seven single nucleotide...

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Source

Identifiers

PMID: 23868022
DOI: 10.1016/j.clinbiochem.2013.07.002

Genes

RAD51
IGFBP7
REST
CFH
HTRA1

Provenance

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