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Current Views on Chr10q26 Contribution to Age-Related Macular Degeneration.

Advances in experimental medicine and biology - 1 Jan 2023

Gogna Navdeep, Hyde Lillian F, Collin Gayle B, Stone Lisa, Naggert Jurgen K, Nishina Patsy M

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of blindness in the global aging population. Familial aggregation and genome-wide association (GWA) studies have identified gene variants associated with AMD, implying a strong genetic contribution to AMD development. Two loci, on human Chr 1q31 and 10q26, respectively, represent the most influential of all genetic factors. While the role of CFH at Chr...

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PMID: 37440010
DOI: 10.1007/978-3-031-27681-1_5

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