Article
Genetic variants within microRNA-binding site of RAD51B are associated with risk of cervical cancer in Chinese women.
Cancer medicine - 1 Sept 2016
Hang Dong, Zhou Wen, Jia Meiqun, Wang Lihua, Zhou Jing, Yin Yin, Ma Hongxia, Hu Zhibin, Li Ni, Shen Hongbin
Abstract excerpt
RAD51B plays a central role in homologous recombinational repair (HRR) of DNA double-strand breaks (DSBs), which is important to prevent genomic instability, a hallmark of cancer. Recent studies suggested that common genetic variants of RAD51B may contribute to cancer susceptibility. In this study, we aimed to investigate whether potentially functional variants within miRNA-binding sites of RAD51B are associated...
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