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Article

rs5888 variant of SCARB1 gene is a possible susceptibility factor for age-related macular degeneration.

PloS one - 5 Oct 2009

Zerbib Jennyfer, Seddon Johanna M, Richard Florence, Reynolds Robyn, Leveziel Nicolas, Benlian Pascale, Borel Patrick, Feingold Josué, Munnich Arnold, Soubrane Gisèle, Kaplan Josseline, Rozet Jean-Michel, Souied Eric H

Abstract excerpt

Major genetic factors for age-related macular degeneration (AMD) have recently been identified as susceptibility risk factors, including variants in the CFH gene and the ARMS2 LOC387715/HTRA1locus. Our purpose was to perform a case-control study in two populations among individuals who did not carry risk variants for CFHY402H and LOC387715 A69S (ARMS2), called "study" individuals, in order to identify new genetic...

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Source

Open in PubMed Open full text

Identifiers

PMID: 19806217
DOI: 10.1371/journal.pone.0007341
PMCID: PMC2752725

Genes

SCARB1
ARMS2
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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