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Article

Dual and beneficial roles of macrophages during skeletal muscle regeneration.

Exercise and sport sciences reviews - 1 Jan 2009

Chazaud Bénédicte, Brigitte Madly, Yacoub-Youssef Houda, Arnold Ludovic, Gherardi Romain, Sonnet Corinne, Lafuste Peggy, Chretien Fabrice

Abstract excerpt

Macrophages are necessary for skeletal muscle regeneration after injury. Muscle recruits inflammatory monocytes/macrophages that switch toward an anti-inflammatory profile upon phagocytosis of debris. In vitro, proinflammatory macrophages stimulate myoblast proliferation, whereas anti-inflammatory macrophages stimulate their differentiation. Thus, macrophages are involved in both phases of skeletal muscle...

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PMID: 19098520
DOI: 10.1097/JES.0b013e318190ebdb

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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