Article
Splicing factor mutations and cancer.
Wiley interdisciplinary reviews. RNA - 1 Jan 2000
Yoshida Kenichi, Ogawa Seishi
Abstract excerpt
Recent advances in high-throughput sequencing technologies have unexpectedly revealed that somatic mutations of splicing factor genes frequently occurred in several types of hematological malignancies, including myelodysplastic syndromes, other myeloid neoplasms, and chronic lymphocytic leukemia. Splicing factor mutations have also been reported in solid cancers such as breast and pancreatic cancers, uveal...
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