Article
Estimating the Heritability of Structural and Functional Brain Connectivity in Families Affected by Attention-Deficit/Hyperactivity Disorder.
JAMA psychiatry - 1 Jan 2017
Sudre Gustavo, Choudhuri Saadia, Szekely Eszter, Bonner Teighlor, Goduni Elanda, Sharp Wendy, Shaw Philip
Abstract excerpt
IMPORTANCE: Despite its high heritability, few risk genes have been identified for attention-deficit/hyperactivity disorder (ADHD). Brain-based phenotypes could aid gene discovery. There is a myriad of structural and functional connections that support cognition. Disruption of such connectivity is a key pathophysiologic mechanism for ADHD, and identifying heritable phenotypes within these connections could...
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