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Article

Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation.

eLife - 11 Feb 2014

Langemeyer Lars, Nunes Bastos Ricardo, Cai Yiying, Itzen Aymelt, Reinisch Karin M, Barr Francis A

Abstract excerpt

Ras superfamily GTPase activation and inactivation occur by canonical nucleotide exchange and GTP hydrolysis mechanisms. Despite conservation of active-site residues, the Ras-related Rab GTPase activation pathway differs from Ras and between different Rabs. Analysis of DENND1-Rab35, Rabex-Rab5, T...

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Identifiers

PMID: 24520163
DOI: 10.7554/eLife.01623
PMCID: PMC3919270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24520163-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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