Article
Polygenic type 2 diabetes prediction at the limit of common variant detection.
Diabetes - 1 Jun 2014
Vassy Jason L, Hivert Marie-France, Porneala Bianca, Dauriz Marco, Florez Jose C, Dupuis Josée, Siscovick David S, Fornage Myriam, Rasmussen-Torvik Laura J, Bouchard Claude, Meigs James B
Abstract excerpt
Genome-wide association studies (GWAS) may have reached their limit of detecting common type 2 diabetes (T2D)-associated genetic variation. We evaluated the performance of current polygenic T2D prediction. Using data from the Framingham Offspring (FOS) and the Coronary Artery Risk Development in...
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