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Article

CpG island methylator phenotype and its association with malignancy in sporadic duodenal adenomas.

Epigenetics - 1 May 2014

Sun Lifeng, Guzzetta Angela A, Fu Tao, Chen Jinming, Jeschke Jana, Kwak Ruby, Vatapalli Rajita, Baylin Stephen B, Iacobuzio-Donahue Christine A, Wolfgang Christopher L, Ahuja Nita

Abstract excerpt

CpG island methylator phenotype (CIMP) has been found in multiple precancerous and cancerous lesions, including colorectal adenomas, colorectal cancers, and duodenal adenocarcinomas. There are no reports in the literature of a relationship between CIMP status and clinicopathologic features of sporadic duodenal adenomas. This study sought to elucidate the role of methylation in duodenal adenomas and correlate it...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, p16

Share to Proto-Oncogene Proteins B-raf

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Identifiers

PMID: 24518818
DOI: 10.4161/epi.28082
PMCID: PMC4063833

Genes

BRAF
KRAS
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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