Article
PIK3CA mutations in mucinous cystic neoplasms of the pancreas.
Pancreas - 1 Mar 2014
Garcia-Carracedo Dario, Chen Zong-Ming, Qiu Wanglong, Huang Alicia S, Tang Sophia M, Hruban Ralph H, Su Gloria H
Abstract excerpt
OBJECTIVES: Mucinous cystic neoplasms (MCNs) are rare, potentially curable, mucin-producing neoplasms of the pancreas. We have previously reported PIK3CA (phosphoinositide-3-kinase catalytic subunit, p110α) mutations in intraductal papillary mucinous neoplasms, another mucin-producing neoplasm of the pancreas. In this study, we analyzed the presence of PIK3CA and AKT1/PKB (V-akt murine thymoma viral oncogene...
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