Article
Molecular profiling of <i>Mycobacterium tuberculosis</i> identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c
10 Feb 2014
Abstract excerpt
To identify lipids with roles in tuberculosis disease, we systematically compared the lipid content of virulent Mycobacterium tuberculosis with the attenuated vaccine strain Mycobacterium bovis bacillus Calmette-Guérin. Comparative lipidomics analysis identified more than 1,000 molecular differences, including a previously unknown, Mycobacterium tuberculosis-specific lipid that is composed of a diterpene unit...
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