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Heterologous production of 1-tuberculosinyladenosine in <i>Mycobacterium kansasii</i> models pathoevolution towards the transcellular lifestyle of <i>Mycobacterium tuberculosis</i>

2020-04-26

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium kansasii is an environmental non-tuberculous mycobacterium that causes opportunistic tuberculosis-like disease. It is one of the most closely related species to the M. tuberculosis complex. Using M. kansasii as a proxy for the M. kansasii-M. tuberculosis -common ancestor, we asked whether introducing the M. tuberculosis -specific gene pair Rv3377c-Rv3378c into M. kansasii aff...

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Literature Corpus work
817a14f2-3361-55dc-aa0e-a53b7ff083dc
DOI
10.1101/2020.04.25.060590
Open publication

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