Article
Phenotypic determination and characterization of nestin-positive precursors derived from human fetal pancreas.
Laboratory investigation; a journal of technical methods and pathology - 1 Apr 2003
Huang Haixia, Tang Xueming
Abstract excerpt
Demand for donations to meet the requirements of pancreas or islet transplantation has prompted the search for alternative sources of beta-cell replacement therapy. Earlier studies identified nestin-positive islet-derived progenitor cells (NIPs) residing in human pancreas. In the present study, we isolated and cultured human fetal NIPs that express stem cell marker ABCG2/BCRP1. In confluent cultures, NIPs formed...
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