Article
CES1A -816C as a genetic marker to predict greater platelet clopidogrel response in patients with percutaneous coronary intervention.
Journal of cardiovascular pharmacology - 1 Feb 2014
Zou Jian-Jun, Chen Shao-Liang, Fan Hong-Wei, Tan Jie, He Bang-Shun, Xie Hong-Guang
Abstract excerpt
This study was designed to determine whether CES1A -816A/C polymorphism could be associated with altered clopidogrel response. Recruited patients were pretreated with 300 mg clopidogrel loading dose before undergoing percutaneous coronary intervention for stenting and genotyped with CYP2C19 *2, *3, or *17, and CES1A -816A/C, respectively. Adenosine diphosphate-induced maximum platelet aggregation (MPA) was...
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