Article
Efffect of the ABCC3 -211C/T polymorphism on clopidogrel responsiveness in patients with percutaneous coronary intervention.
Clinical and experimental pharmacology & physiology - 1 Aug 2013
Zou Jian-Jun, Fan Hong-Wei, Chen Shao-Liang, Tan Jie, He Bang-Shun, Xie Hong-Guang
Abstract excerpt
Multidrug resistance protein 3 (MPR3), encoded by the ATP-binding cassette, subfamily C (CFTR/MRP), member 3 (ABCC3) gene, functions as an important drug efflux transporter. The ABCC3 -211C/T polymorphism is associated with decreased MRP3 mRNA expression, and low MRP3 mRNA expression is associate...
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