Article
Evaluation of whole genome sequencing for outbreak detection of Salmonella enterica.
PloS one - 1 Jan 2014
Leekitcharoenphon Pimlapas, Nielsen Eva M, Kaas Rolf S, Lund Ole, Aarestrup Frank M
Abstract excerpt
Salmonella enterica is a common cause of minor and large food borne outbreaks. To achieve successful and nearly 'real-time' monitoring and identification of outbreaks, reliable sub-typing is essential. Whole genome sequencing (WGS) shows great promises for using as a routine epidemiological typing tool. Here we evaluate WGS for typing of S. Typhimurium including different approaches for analyzing and comparing...
Topics
- DNA, Bacterial
- Disease Outbreaks
- Genome, Bacterial
- Genome-Wide Association Study
- Phylogeny
- Polymorphism, Single Nucleotide
- Salmonella Infections
- Salmonella enterica
- Sequence Analysis, DNA