Article
Enhancing genomics-based outbreak detection of endemic Salmonella enterica serovar Typhimurium using dynamic thresholds.
Microbial genomics - 1 Jun 2021
Payne Michael, Octavia Sophie, Luu Laurence Don Wai, Sotomayor-Castillo Cristina, Wang Qinning, Tay Alfred Chin Yen, Sintchenko Vitali, Tanaka Mark M, Lan Ruiting
Abstract excerpt
Salmonella enterica serovar Typhimurium is the leading cause of salmonellosis in Australia, and the ability to identify outbreaks and their sources is vital to public health. Here, we examined the utility of whole-genome sequencing (WGS), including complete genome sequencing with Oxford Nanopore technologies, in examining 105 isolates from an endemic multi-locus variable number tandem repeat analysis (MLVA) type...
Topics
- Australia
- DNA, Bacterial
- Disease Outbreaks
- Endemic Diseases
- Genomics
- Humans
- Minisatellite Repeats
- Molecular Epidemiology
- Molecular Typing
- Phylogeny
- Polymorphism, Single Nucleotide
- Public Health
- Salmonella Food Poisoning