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Investigation of insulin resistance gene polymorphisms in patients with differentiated thyroid cancer.

Molecular biology reports - 1 May 2014

Akker Mustafa, Güldiken Sibel, Sipahi Tammam, Palabıyık Orkide, Tosunoğlu Ayhan, Çelik Özlem, Tunçbilek Nermin, Sezer Atakan, Süt Necdet

Abstract excerpt

We aimed to investigate insulin receptor substrate-1 (IRS-1), insulin receptor substrate-2 (IRS-2), insulin-like growth factor binding protein-3 (IGFBP-3) genotypes, which are thought to be involved in the pathogenesis of many solid tumors and have thus far not been studied in patients with differentiated thyroid cancer (DTC). The study consisted of 93 patients diagnosed with DTC (79 females, 14 males) and 111...

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Identifiers

PMID: 24504452
DOI: 10.1007/s11033-014-3218-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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