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Article

10× single-cell sequencing revealed cellular composition heterogeneity in cardiac myxoma with malignant glandular properties.

Microvascular research - 1 Jul 2024

Zhang Li, Qiu Zhi-Huang, Wei Xiaozhen, Yao Mengge, Chen Shao-Kun, He Jian, Ye Jian-Qiang, Li Yu-Mei, Chen Liang-Wan

Abstract excerpt

Cardiac myxoma is the most common primary cardiac tumor in adults. The histogenesis and cellular composition of myxoma are still unclear. This study aims to reveal the role of myxoma cell components and their gene expression in tumor development. We obtained single living cells by enzymatic digestion of tissues from 4 cases of surgically resected cardiac myxoma. Of course, there was 1 case of glandular myxoma and...

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Identifiers

PMID: 38801942
DOI: 10.1016/j.mvr.2024.104697

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