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Exposing the Two Contrasting Faces of STAT2 in Inflammation

25 Jul 2022

Abstract excerpt

Inflammation is a natural immune defense mechanism of the body's response to injury, infection, and other damaging triggers. Uncontrolled inflammation may become chronic and contribute to a range of chronic inflammatory diseases. Signal transducer and activator of transcription 2 (STAT2) is an essential transcription factor exclusive to type I and type III interferon (IFN) signaling pathways. Both pathways are...

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PMID: 35877097
DOI: 10.1089/jir.2022.0117

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