Article
PRODH polymorphisms, cortical volumes and thickness in schizophrenia.
PloS one - 1 Jan 2014
Ota Vanessa K, Bellucco Fernanda T, Gadelha Ary, Santoro Marcos L, Noto Cristiano, Christofolini Denise M, Assunção Idaiane B, Yamada Karen M, Ribeiro-dos-Santos Andrea K, Santos Sidney, Mari Jair J, Smith Marília A C, Melaragno Maria I, Bressan Rodrigo A, Sato João R, Jackowski Andrea P, Belangero Sintia I
Abstract excerpt
Schizophrenia is a neurodevelopmental disorder with high heritability. Several lines of evidence indicate that the PRODH gene may be related to the disorder. Therefore, our study investigates the effects of 12 polymorphisms of PRODH on schizophrenia and its phenotypes. To further evaluate the roles of the associated variants in the disorder, we have conducted magnetic resonance imaging (MRI) scans to assess...
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