Article
Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2003
Williams H J, Williams N, Spurlock G, Norton N, Zammit S, Kirov G, Owen M J, O'Donovan M C
Abstract excerpt
People with deletion of the chromosome 22q11 region associated with velo cardio-facial syndrome (VCFS) have a remarkably high risk of developing schizophrenia. Recently, the gene proline dehydrogenase (PRODH) which maps to 22q11 and is also an excellent functional candidate gene for psychosis, has been reported to show genetic association with schizophrenia. We have screened all the exons and adjacent intronic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
