Article

Characterization of DNA methylation in PBMCs and donor-matched iPSCs shows methylation is reset during stem cell reprogramming

2024-12-13

Abstract excerpt

<h4>Summary</h4> DNA methylation is an important epigenetic mechanism that helps define and maintain cellular functions. It is influenced by many factors, including environmental exposures, genotype, cell type, sex, and aging. Since age is the primary risk factor for developing neurodegenerative diseases, it is important to determine if aging-related DNA methylation is retained when cells are reprogrammed to an i...

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Literature Corpus work: 809af4fd-cb02-5a01-b70e-e54ef6cefb05
DOI: 10.1101/2024.12.13.627515

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