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Article

Association of ABCB1 gene polymorphisms and haplotypes with therapeutic efficacy of glucocorticoids in Chinese patients with immune thrombocytopenia.

Human immunology - 1 Apr 2014

Xuan Min, Li Huiyuan, Fu Rongfeng, Yang Yanhui, Zhang Donglei, Zhang Xian, Yang Renchi

Abstract excerpt

Resistance to glucocorticoids (GCs) remains a tricky problem complicating the therapy of ITP. Recently, ATP binding cassette gene B1 gene (ABCB1) was reported to be correlated with susceptibility and therapeutic efficacy of autoimmune diseases through P-glycoprotein (Pgp). We investigated three single nucleotide polymorphisms (SNPs) of ABCB1 and their haplotypes by PCR-RFLP (restriction fragment length...

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Source

Identifiers

PMID: 24486577
DOI: 10.1016/j.humimm.2014.01.013

Genes

ABCB1
CAT
TAT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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