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Article

Can we predict unresponsiveness to methotrexate in rheumatoid arthritis? A pharmacogenetic study.

Inflammopharmacology - 1 Feb 2022

Melikoglu Meltem Alkan, Balkan Eda

Abstract excerpt

OBJECTIVE: Methotrexate (MTX) is the anchor drug in the treatment of rheumatoid arthritis (RA) and the therapeutic response to MTX has been observed to vary widely among these patients. The aim of this study was to investigate ABCB1 gene (the multidrug resistant 1 gene; MDR1 gene) polymorphism in patients with RA and to evaluate the relation between MTX unresponsiveness and this polymorphism. METHODS: Forty-five...

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Share to Antirheumatic Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35043269
DOI: 10.1007/s10787-021-00921-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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