Article
Association study of glucocorticoid receptor genetic polymorphisms with efficacy of glucocorticoids in systemic lupus erythematosus: a prospective cohort study.
Autoimmunity - 1 Dec 2013
Zou Yan-Feng, Xu Jian-Hua, Wang Fen, Liu Shuang, Tao Jin-Hui, Cai Jing, Lian Li, Xiao Hui, Chen Pei-Ling, Tian Guo, Wu Min, Wang De-Guang, Liu Sheng-Xiu, Liang Chun-Mei, Pan Fa-Ming, Su Hong, Pan Hai-Feng, Ye Dong-Qing
Abstract excerpt
The response to glucocorticoids (GCs) for patients with systemic lupus erythematosus (SLE) is characterized by wide interindividual variability, with a significant number of patients who have no response. We analyzed whether genetic polymorphisms within glucocorticoid receptor (GR) gene are related to variability in the efficacy of GCs in Chinese population with SLE. A cohort of 220 patients with SLE was studied....
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