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Article

Contribution of MDR1 gene polymorphisms on IBD predisposition and response to glucocorticoids in IBD in a Chinese population.

Journal of digestive diseases - 1 Jan 2015

Yang Qing Fan, Chen Bai Li, Zhang Qing Sen, Zhu Zhen Hua, Hu Bin, He Yao, Gao Xiang, Wang Yi Ming, Hu Pin Jin, Chen Min Hu, Zeng Zhi Rong

Abstract excerpt

OBJECTIVE: The cornerstone of conventional treatment for inflammatory bowel disease (IBD) is glucocorticoid (GC). Single nucleotide polymorphisms (SNPs) of genes such as multidrug resistance 1 (MDR1) are related to patient's response to GC, and MDR1 polymorphisms are associated with susceptibility to IBD in Caucasians. We aimed to investigate whether the polymorphisms of five genes including MDR1 influence the...

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Identifiers

PMID: 25346426
DOI: 10.1111/1751-2980.12205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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