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Article

Genetically engineered ERα-positive breast cancer mouse models

30 Jan 2014

Abstract excerpt

The majority of human breast cancers are estrogen receptor-positive (ER+), but this has proven challenging to model in genetically engineered mice. This review summarizes information on 21 mouse models that develop ER+ mammary cancer. Where available, information on cancer pathology and gene expression profiles is referenced to assist in understanding which histological subtype of ER+ human cancer each model...

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Identifiers

PMID: 24481326
DOI: 10.1530/erc-13-0512

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